Selected Publications

Members of Lobingier Lab Underlined

 

Profiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors Palacco BJ#, Lobingier BT#, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Herandez A, Xu J, Li Q, Novy B, Ning Z, Schoichet B, Levitz J, Korean N, von Zastrow M, Huttenhain R (# equal contributors) Nature Chemical Biology, 2024

A genome-wide CRISPR interference screen using an engineered trafficking biosensor reveals a role for RME-8 in opioid receptor regulation Novy B, Adoff H, De Maria M, Kampann M, Tsvetanova NG, von Zastrow M, Lobingier BT. BioRvix, 2022

Ligand-directed labeling of opioid receptors for covalent attachment of fluorophores or small molecule probes Adoff H#, Halls VS#, Holland E#, Lobingier BT*, Arttamangkul S* (# equal contributors; * co-lead contacts) Star Protocols. 2023

GPCRs at Endosomes: sorting, Signaling, and Recycling. Irannejad R and Lobingier BT Book Chapter: GPCRs as Therapeutic Targets, Gilchrist (Ed). 2022

A cellular perspective of bias at G protein-coupled receptors. Fernandez TJ, De Maria M, Lobingier BT Protein Science. 2020

When trafficking and signaling mix: How subcellular location shapes G protein-coupled receptor activation of heterotrimeric G proteins. Lobingier BT and von Zastrow M. Traffic. 2019

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action. Stoeber M, Jullié D, Lobingier BT, Laeremans T, Steyaert J, Schiller PW, Manglik A, von Zastrow M. Neuron. 2018

An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells. Lobingier BT#, Hüttenhain R#, Eichel K, Miller KB, Ting AY, von Zastrow M, Krogan NJ. (# equal contributors) Cell. 2017

Effects of endocytosis on receptor-mediated signaling. Irannejad R, Tsvetanova NG, Lobingier BT, von Zastrow M. Curr Opin Cell Biol. 2015